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Metabolic dysfunction-associated steatotic liver disease

Year: 2025

Type: article

Abstract: Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly non-alcoholic fatty liver disease (NAFLD), poses a significant challenge to public health. With the rise of obesity, hepatic steatosis now affects around a third of the UK population to varying degrees, frequently coexisting with other cardiometabolic conditions such as type 2 diabetes and ischaemic heart disease. Most patients with MASLD will be diagnosed in the community through investigation of deranged liver function tests or incidentally on abdominal ultrasound. It is therefore important for the general physician to be able to diagnose and risk-stratify MASLD, ensuring appropriate management and onward referral to hepatology for individuals with moderate or high risk of fibrosis.

Source: Clinical Medicine

DOI: 10.1016/j.clinme.2025.100526

Authors: Catherine Hsu, William Alazawi

Institution: Queen Mary University of London

Language: English

Topic: Liver Disease Diagnosis and Treatment

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,500