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Nasal Iodophor to Reduce Candidozyma auris Nasal Carriage in Nursing Home Residents

Year: 2025

Type: article

Study design: Clinical Trial

Abstract: Candidozyma auris is an emerging drug-resistant yeast that frequently colonizes the nose. Among 27 nursing home residents, 5 days of twice-daily nasal iodophor (10% povidone iodine) reduced nasal carriage bioburden in 14 (52%), with negative posttreatment cultures in 5 (19%), providing hypothesis-generating evidence for the role of nasal decolonization in C auris prevention.

Source: Open Forum Infectious Diseases

DOI: 10.1093/ofid/ofaf650

Authors: Gabrielle M Gussin, Ken Kleinman, Raveena D Singh, Raheeb Saavedra, Eric Nguyen, Julie A Shimabukuro, Cassiana E Bittencourt, Susan S Huang

Institutions: University of California, Irvine, University of Massachusetts Amherst, University of California, Irvine Medical Center, UC Irvine Health

Language: English

Topic: Antifungal resistance and susceptibility

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $4,053

Funder: National Institute of Allergy and Infectious Diseases

Awards: G7840369711, MDRO Carriage, Transmission, Sequelae, and Prevention in Nursing Homes

OpenAlex ID: W4415533907

FWCI: 2.126

Cites: 13

Cited by: 3

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