Work

Strongyloides stercoralis infection presenting as a surgical diagnosis, a rare but important consideration: Case series of two patients

Year: 2025

Type: article

Abstract: Strongyloides stercoralis is a parasitic helminth with variable gastrointestinal symptoms that can mimic inflammatory bowel disease or malignancy. Diagnosis is often delayed due to nonspecific presentation and low test sensitivity, especially in non-endemic areas. We reviewed two cases of Strongyloides stercoralis infection presenting as chronic colitis. Clinical, endoscopic, and histologic findings were analyzed, and diagnosis was confirmed via serology testing. Both patients presented with chronic abdominal pain and colitis on image test. Serological tests revealed immune responses consistent with Strongyloides . One patient had a history of travel to an endemic area; the other had chronic alcohol use. Symptoms resolved with antiparasitic therapy. Strongyloides infection can mimic chronic colitis and lead to misdiagnosis. Awareness of risk factors and histologic features is essential to avoid unnecessary surgical intervention. • Strongyloides infection can present with chronic gastrointestinal symptoms that closely mimic inflammatory bowel disease. • Diagnosis is challenging due to nonspecific clinical features, absence of eosinophilia, and low sensitivity of stool microscopy. • Early recognition and treatment with antiparasitic therapy can prevent complications and avoid unnecessary surgical intervention.

Source: International Journal of Surgery Case Reports

DOI: 10.1016/j.ijscr.2025.112090

Authors: Martin Infante Altamirano, Akshat Sanan, Gustavo A. Rubio, Henry J. Lujan

Institutions: Peruvian University of Applied Sciences, Jackson Health System

Language: English

Topic: Parasites and Host Interactions

Subfield: Parasitology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,090