Work

Predictors of intraoperative donor heart turndown after initial acceptance for transplantation

Year: 2025

Type: article

Abstract: Objective: Because of the low use of potential heart donors, it is important to maximize transplantation and minimize discard of accepted offers. We analyzed national registry data to investigate risk factors for intraoperative turndown of donor hearts that were initially accepted for transplantation. Methods: < .2 on univariate analysis. Results: < .001). Additional independent risk factors included left ventricular ejection fraction ≤50%, >10 transfusions during terminal hospitalization, Hispanic and Other (vs White) race/ethnicity, death attributable to stroke, and hypertension. Conclusions: We identified several factors associated with intraoperative turndown that can inform anticipatory intraoperative evaluation and team coordination while preserving access to donor hearts.

Source: JTCVS Open

DOI: 10.1016/j.xjon.2025.09.049

Authors: Armaan F. Akbar, Alice L. Zhou, Jessica M. Ruck, Sorush Rokui, Dane Paneitz, Ahmet Kilic

Institutions: Johns Hopkins University, Johns Hopkins Hospital

Language: English

Topic: Transplantation: Methods and Outcomes

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,431