Work

Bioresorbable Stent in Newborn With Pulmonary Stenosis and Duct-Dependent Pulmonary Circulation

Year: 2025

Type: article

Abstract: BACKGROUND: Critical pulmonary valve stenosis is a rare congenital heart defect that causes cyanosis in the newborn and is characterized by severe narrowing of the right ventricular outflow tract and pulmonary valve, leading to restricted pulmonary blood flow. FIRST-IN-HUMAN/EARLY REPORTS SUMMARY: We present the case of a full-term male infant diagnosed with critical pulmonary stenosis with ductal-dependent pulmonary circulation. The patient underwent successful percutaneous pulmonary valvuloplasty and ductal stenting with a new iron-based bioresorbable stent (IBS Angel, Biotyx Medical). Postoperative evaluation was favorable. DISCUSSION: This combined strategy ensured effective right ventricular decompression and maintenance of pulmonary blood flow. NOVELTY: This is to our knowledge the first case in Europe on the use of a bioresorbable stent to maintain ductal patency in critical pulmonary stenosis with dual pulmonary blood supply. TAKE-HOME MESSAGES: Bioresorbable stents may represent a safe short- to medium-term option in selected neonates with ductal-dependent pulmonary circulation. Early outcomes appear favorable, but longer follow-up is warranted.

Source: JACC Case Reports

DOI: 10.1016/j.jaccas.2025.105845

Authors: Carlo Barsali, Micol Rebonato, Enrico Piccinelli, Lisa Bianco, Mara Pilati, Gianfranco Butera

Institutions: Bambino Gesù Children's Hospital, Sapienza University of Rome, Istituti di Ricovero e Cura a Carattere Scientifico

Language: English

Topic: Congenital Heart Disease Studies

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $850