Work

Newly identified oncolytic VSV-GP-specific CD8+ T cell epitopes for monitoring of anti-viral immune responses in the BALB/c mouse model

Year: 2025

Type: article

Abstract: T cells, which will aid the preclinical development of novel VSV-GP variants. This epitope-specific monitoring also serves as proof of concept for the potential future application of anti-viral immunomonitoring in clinical trial settings.

Source: Molecular Therapy Oncology

DOI: 10.1016/j.omton.2025.201072

Authors: Sarah Danklmaier, Saskia V. Vijver, Lisa Pipperger, Gabriel Floriani, Lukas Perro, Vanessa Konrad, Tamara Hofer, Hubert Hackl, Krishna Das, Guido Wollmann

Institutions: Innsbruck Medical University, Universität Innsbruck, Tyrolean Cancer Research Institute

Language: English

Topic: Virus-based gene therapy research

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,900

Funders: Boehringer Ingelheim, Österreichische Forschungsförderungsgesellschaft, Christian Doppler Forschungsgesellschaft

Award: G6961942174

OpenAlex ID: W4415540759

FWCI:

Cites: 60

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