Work

Bronchial anastomotic infection after lung transplantation – An interdisciplinary review

Year: 2025

Type: article

Abstract: Airway complications (AC) are an important cause of morbidity and mortality post-lung transplantation (LTx). Bronchial anastomotic infection (BAI) is a complication as well as a risk factor for progressive AC post-lung transplantation. The two are closely related and difficult to untangle. AC affects approximately one in ten LTx-recipients, while BAI is reported in around one in thirty LTx-recipients. Associated bacterial pathogens frequently include Pseudomonas aeruginosa and other gram-negative pathogens, while the most frequent reported fungal pathogen is Aspergillus spp. . Associated complication rates are reported to be high. Although the epidemiology and outcome of AC have been investigated, there is an important lack of BAI-specific literature. The incidence, risk factors, treatment and prevention of BAI are not well known. To close this knowledge gap and to ultimately improve prevention, management and outcome; interdisciplinary investigations and prospective studies are warranted.

Source: JHLT Open

DOI: 10.1016/j.jhlto.2025.100417

Authors: Etienne Abdelnour-Berchtold, Pieter-Jan Gijs, Angela Koutsokera, Laura N. Walti

Institutions: Centre Hospitalier Universitaire Vaudois, University of Lausanne, University of Bern, University Hospital of Bern

Language: English

Topic: Transplantation: Methods and Outcomes

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,500