Work

Ultra‐wideband raster‐scanning optoacoustic mesoscopy as a histologic‐grade tool for melanoma depth assessment

Year: 2025

Type: article

Abstract: Depth versus resolution of non-invasive skin imaging modalities.Comparative visualization of the imaging depth (x-axis, in millimetres) and spatial resolution (y-axis, in micrometres) for non-invasive skin imaging technologies.Reflectance confocal microscopy achieves the highest resolution but is limited to superficial depths.Line-field confocal optical coherence tomography provides similar resolution with slightly improved penetration.Optical coherence tomography offers more depth with reduced resolution.Raster-scanning optoacoustic mesoscopy (RSOM) balances high-resolution and deeper imaging, while high-frequency ultrasound achieves the greatest depth but with limited resolution.RSOM occupies a unique position in the imaging spectrum, bridging the gap between cellular resolution and histology-level depth.HFUS, high-frequency ultrasound;

Source: Journal of the European Academy of Dermatology and Venereology

DOI: 10.1111/jdv.20895

Authors: Norbert Kiss, Mehdi Boostani

Institutions: Semmelweis University, Roswell Park Comprehensive Cancer Center

Language: English

Topic: Photoacoustic and Ultrasonic Imaging

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $5,450