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Paper-based sensing of cinnamic ortho-diphenols in food samples using photoluminescent laser-induced aluminum nanostructures

Year: 2025
Type: article
Abstract: A versatile CO 2 laser plotter-based strategy is proposed to obtain optically active aluminum/paper nanostructures for the selective colorimetric sensing of cinnamic ortho-diphenolic compounds (o-PCs). The Laser synthesis generated Al nanostructures (L-Al) that were characterized, demonstrating photoluminescent properties. A L-Al Photoluminescent Paper-based Platform (L-Al 3xP ) with an ELISA plate like format, manufactured via accessible benchtop technologies, was conceived to work with a smartphone-readout. The L-Al 3xP sensing relies on chelation-enhanced fluorescence turn-on, driven by the interaction between L-Al sensing spots and o-PCs, which results in a green brightness increase. The L-Al 3xP sensing mechanism and class-selectivity were investigated towards 23 phenolic compounds of different chemical classes; the analytical figures of merits were extrapolated for caffeic, rosmarinic, and chlorogenic acids, highlighting linear dose-response (R 2 ≥ 0.990) and LODs≤3.0 μM. The L-Al 3xP was challenged for o-PCs determination in 15 different food samples, returning reproducible outputs (RSD ≤ 11.1 %, n = 3) well correlated with HPLC-MS/MS ( r = 0.993). • Aluminum-nanostructures were induced on paper via CO 2 laser scribing. • Al-paper nanostructures (L-Al) demonstrate photoluminescent features. • L-Al returns complexation-enhanced fluorescence (CHEF) with cinnamic ortho-diphenols. • CHEF was employed for colorimetric sensing using an L-Al equipped paper device. • Cinnamic ortho-diphenols were successfully determined in different food samples.
DOI: 10.1016/j.foodchem.2025.146826
Language: English
Open Access status: hybrid
Estimated APC paid: $4,930
OpenAlex ID: W4415546351
FWCI: 0.723
Cites: 37
Cited by: 3
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