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Unveiling the gut connection: Exploring the link between microbiota and type 1 diabetes onset in pediatric patients

Year: 2025

Type: article

Abstract: (r=-0.4241, P=0.0492). C-reactive protein levels were negatively associated with Bacteroides (r=-0.4331, P=0.0498). These findings highlighted the role of gut microbiota in pancreatic inflammation and T1DM progression. In conclusion, dysbiosis of children with T1DM was correlated with younger age and a more severe onset. Microbial metabolites levels differed in these patients compared with the healthy control group. To the best of our knowledge, the present study is the first to assess gastrointestinal dysbiosis in T1DM.

Source: Biomedical Reports

DOI: 10.3892/br.2025.2074

Authors: Amalia Arhire, Teodora Papuc, Sorin Ioacără, Gratiela Pircalabioru, Carmen Barbu

Institutions: Carol Davila University of Medicine and Pharmacy, University of Bucharest

Language: English

Topic: Gut microbiota and health

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4415577654

FWCI: 0.779

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Cited by: 3

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