Work

Usefulness of monocyte distribution width (MDW) in enhancing diagnostic accuracy of infection among severely ill patients presenting to the emergency department

Year: 2025

Type: article

Abstract: Sepsis remains a major cause of morbidity and mortality and continues to pose substantial diagnostic challenges in its early stages. Monocyte Distribution Width (MDW), a parameter automatically integrated into complete blood counts by next-generation haematology analysers, has emerged as a promising biomarker. This study evaluates the diagnostic performance of MDW compared with traditional markers (C-reactive protein and leukocyte count) and clinical scoring systems (SOFA and NEWS) in a cohort of critically ill patients presenting to a hospital emergency department, with the aim of distinguishing those with infection from those whose severity was attributable to other causes.

Source: Revista Española de Quimioterapia

DOI: 10.37201/req/s01.01.2025

Authors: Juan González del Castillo, Enrique del Toro, Marcos Fragiel, David Oteo, Ana García-Álvarez

Institutions: Universidad Complutense de Madrid, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos

Language: English

Topic: Sepsis Diagnosis and Treatment

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4415586964

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