Work

Acute Pancreatitis Following Diagnostic Oesophagogastroduodenoscopy: A Rare Post-procedure Complication

Year: 2025

Type: article

Abstract: Acute pancreatitis is a recognised complication of endoscopic retrograde cholangiopancreatography (ERCP), but its occurrence after diagnostic oesophagogastroduodenoscopy (OGD) is exceedingly rare. We report a case of a woman who developed acute pancreatitis shortly after a diagnostic OGD during which a small peri-ampullary mucosal prominence was inadvertently biopsied. She presented with acute epigastric pain and was found to have imaging features consistent with pancreatitis in the absence of gallstones, alcohol use, or other causes. The patient was managed conservatively with intravenous fluids, analgesia, and gradual reintroduction of diet, leading to full clinical and radiological recovery. This case highlights an uncommon but important iatrogenic complication of diagnostic endoscopy and underscores the need for caution when performing biopsies near the ampulla of Vater, where minor trauma may precipitate transient pancreatic duct obstruction and pancreatitis.

Source: Cureus

DOI: 10.7759/cureus.95520

Authors: Smriti Chaudhary, Pranav Jha

Institutions: Imperial College London, Cambridge University Hospitals NHS Foundation Trust

Language: English

Topic: Pancreatitis Pathology and Treatment

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4415593272