Work

FMR1 Premutation Carrier Mothers’ Daily Negative Affect and Cortisol: Probing the Impacts of Stress Exposure, Coping Style, and CGG Repeats

Year: 2025

Type: article

Abstract: This study utilized a daily diary methodology to investigate negative affect and cortisol secretion of mothers of adolescents and adults with fragile X syndrome (n = 104). We investigated whether coping style moderated the effects of child behavior problems on daily stress responses for these mothers and whether mothers with varying numbers of CGG repeats differed in the extent to which their coping style impacted daily outcomes. Results indicated that high levels of problem-focused coping buffered the effects of behavior problems on mothers' negative affect and cortisol secretion. There was a significant interaction between CGG repeat group and coping in predicting negative affect; mothers with midrange CGG repeats were less likely to benefit from coping than those who had fewer repeats.

Source: American Journal on Intellectual and Developmental Disabilities

DOI: 10.1352/1944-7558-130.6.512

Authors: Leann Smith DaWalt, Jinkuk Hong, Catherine Rogers Gaspar, Ashley Woodman, Elizabeth M. Berry-Kravis, Marsha R. Mailick

Institutions: Rush University Medical Center, University of Wisconsin–Madison, University of Massachusetts Amherst

Language: English

Topic: Family and Disability Support Research

Subfield: Clinical Psychology

Field: Psychology

Domain: Social Sciences

SDG: Good health and well-being

Open Access status: green

Funders: University of Wisconsin-Madison, Waisman Center, National Institutes of Health, Eunice Kennedy Shriver National Institute of Child Health and Human Development