Work

On target: antibodies against the neuraminidase active site

Year: 2025

Type: article

Abstract: While often overlooked in studies of influenza antibody responses, the virally encoded neuraminidase (NA) is emerging as an attractive vaccine target due to its comparably high sequence conservation. Recent studies by Jo et al., Lederhofer et al., and Lv et al. reveal a common theme of receptor mimicry mediated by structurally convergent antibodies.

Source: Trends in Microbiology

DOI: 10.1016/j.tim.2025.10.006

Authors: Pradeepa Pushparaj, Gunilla B. Karlsson Hedestam

Institution: Karolinska Institutet

Language: English

Topic: Influenza Virus Research Studies

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $7,030