Work

Mpox-Specific Neutralizing Antibodies up to 9 Months Following 1 or 2 Doses of Intradermal MVA-BN Vaccination in Sweden

Year: 2025

Type: article

Abstract: This study assessed clade IIb monkeypox virus-specific antibody kinetics up to 9 months following intradermal vaccination for mpox, considering previous smallpox vaccination and human immunodeficiency virus status. Neutralizing antibodies waned significantly at 3 and 9 months, in line with previous reports of antibody waning after subcutaneous vaccination. Booster dosing and immunological memory need further study.

Source: Open Forum Infectious Diseases

DOI: 10.1093/ofid/ofaf657

Authors: Carmen Espinosa-Gongora, Wanda Christ, Núria Mayola Danés, Claudia Eichler-Jonsson, Finn Filén, Elisabet Storgärd, Victor Westergren, Jonas Klingström, Sara Gredmark-Russ, Kari Johansen, Anna Mia Ekström, Klara Sondén

Institutions: Public Health Agency of Sweden, European Centre for Disease Prevention and Control, Karolinska Institutet, Stockholm South General Hospital, Linköping University, Karolinska University Hospital

Language: English

Topic: Poxvirus research and outbreaks

Subfield: Virology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $4,053

Funder: Svenska Läkaresällskapet

Award: G7920903825

OpenAlex ID: W4415608806

FWCI: 0.906

Cites: 9

Cited by: 2

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