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Discovery of Novel and Highly Potent Wee1 and HDAC Dual-Target Inhibitors for the Treatment of Acute Myeloid Leukemia

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Year: 2025
Type: article
Source: Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.5c01789
Authors: Wenhui Zhang, Wenxin Yan, Tianyi Wei, Sai Che, Yangqian Sun, Aohua Xiao, Jiayu Wu, Yunzhen Zhan, Hongmei Li, Tao Lu, Yungen Xu, Hongfeng Gu, Hui Huang, Jinsong Han
Institutions: China Pharmaceutical University, State Key Laboratory of Natural Medicine
Language: English

Topic: Histone Deacetylase Inhibitors Research
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: National Natural Science Foundation of China, State Key Laboratory of Natural Medicines, Fundamental Research Funds for the Central Universities, Shenzhen Science and Technology Innovation Program
Awards: G2315666212, G2493075825, G4015091221, G4207287700, G5690382459, G6684909494, G7411279429
OpenAlex ID: W4415612264
FWCI: 0.254
Cites: 70
Cited by: 1
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