Work

Cocoa flavanols alleviate early diastolic dysfunction by decreasing left atrial volume in a randomized double blinded trial in healthy older individuals

Year: 2025

Type: article

Abstract: : We provide evidence that cocoa flavanol intake mitigates early changes of diastolic dysfunction by reversing left atrial and left ventricular remodeling, thus providing novel insights into the mechanisms behind the beneficial cardiovascular effect of flavanol intake. The clinical trial registry number is NCT05782309 (https://clinicaltrials.gov).

Source: Food & Function

Authors: Dragos Andrei Duse, Michael Gröne, Niklas Ophoff, Nicolas Kramser, Hendrik Schweers, Javier Ottaviani, Hagen Schroeter, Christine Quast, Florian Bönner, Christian Heiss, Roberto Sansone, Christian Jung, Malte Kelm, Ralf Erkens

Institutions: Heinrich Heine University Düsseldorf, Mars (United States), University of Surrey

Language: English

Topic: Cardiovascular Function and Risk Factors

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funder: Mars

OpenAlex ID: W4415614985

FWCI: 0.649

Cites: 39

Cited by: 1

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