Work

Botulinum Toxin in the Therapy of Chronic or Relapsing Plantar Fasciitis—A Descriptive Review

Year: 2025

Type: article

Abstract: Background. Plantar fasciitis is a degenerative condition that may follow a chronic or recurrent course. Injectable agents are frequently employed to alleviate pain and restore function. Recently, botulinum toxin (BoNT) has gained particular attention for its analgesic properties, positioning it as a promising therapeutic option for the management of plantar fasciitis. Method. We conducted a literature review to evaluate studies on BoNT administration in plantar fasciitis, aiming to define the target tissues, optimal doses, methods of administration, and associated adverse effects. Results. The evidence suggests that BoNT provides significant short- and long-term analgesic benefits when administered either intrafascially or intramuscularly, with outcomes comparable to or exceeding those of corticosteroids. Conclusion. Further high-quality studies are warranted to compare BoNT with other therapeutic modalities, such as PRP and extracorporeal shockwave therapy (ESWT).

Source: Biomedicines

DOI: 10.3390/biomedicines13112647

Authors: Daniela Poenaru, Claudia-Gabriela Potcovaru, Andreea Dumitrescu, Livia Alexandra Ion, Roxana Nartea, Delia Cinteza

Institution: Carol Davila University of Medicine and Pharmacy

Language: English

Topic: Botulinum Toxin and Related Neurological Disorders

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,137