Year: 2025
Type: article
Abstract: For the first time, this study presents the phytochemical and anticancer activity studies on Sphagnum molle species. Chemical component analysis of S. molle plant was carried out by HPLC/TOF-MS. Anticancer activity studies of its organic solvent extract against human prostate cancer (PC3) cells were performed. Chlorogenic acid, along with gentisic, 4-hydroxy-benzoic, protocatechic, vanillic, chicoric, ferulic, and cinnamic acids, 4-hydroxybenzaldehyde, and rutin, were identified as the main components in S. molle extract. In the antiproliferative activity studies of MeOH:CHCl3 extract of S. molle plant, high dose was found to show the highest activity against human prostate cancer (PC3) cells with a 68% inhibition between the 10th and 15th hours.
Authors: Muhammed Altun, Serkan Koldaş
Institution: Çankırı Karatekin University
Language: English
Subfield: Plant Science
Domain: Life Sciences
Open Access status: diamond
Funder: Çankiri Karatekin Üniversitesi
OpenAlex ID: W4415630355