Year: 2025
Type: article
Abstract: High Resolution Image Download MS PowerPoint Slide Accurate temperature measurements are important for cancer diagnosis, as localized temperature variations are often indicative of pathological conditions such as cancer and inflammation. The Nd 3+ -Yb 3+ system is particularly promising due to its efficient energy transfer under 808 nm excitation, leading to distinct emissions from both ions in the second biological window (NIR-II, 1000–1700 nm). This spectral region is ideal for deep tissue imaging and temperature sensing, as it offers reduced scattering and absorption by biological tissues, enabling higher penetration depths and improved signal-to-noise ratios. This study presents a new hybrid thermometer composed of a silica core and a periodic mesoporous organosilica (PMO) shell decorated with LiLuF 4:Nd 3+, Yb 3+ nanoparticles, enabling temperature sensing and imaging in the NIR-II range. Additionally, these hybrid thermometers demonstrate drug release potential upon loading with doxorubicin as a model drug, indicating potential theranostic applications.
Source: ACS Omega
Authors: Sonali Mohanty, Mirijam Lederer, Jorge García-Balduz, Simona Premcheska, Andre G. Skirtach, Kristof Van Hecke, Anna M. Kaczmarek
Institution: Ghent University
Language: English
Subfield: Materials Chemistry
Field: Materials Science
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $1,935
OpenAlex ID: W4415640927