Work

Cerebral blood flow trajectories in paediatric sickle cell anaemia by age, region, and treatment associations

Year: 2025

Type: article

Abstract: Opposite to the age trend in healthy children, cerebral blood flow increases with age in children with sickle cell anaemia. Early treatment with hydroxyurea (hydroxycarbamide) may help slow this abnormal trend and protect brain functions.

Source: British Journal of Haematology

DOI: 10.1111/bjh.70224

Authors: Ping Zou Stinnett, Robert J. Ogg, Kathleen Helton, Winfred Wang, Andrew M. Heitzer, Zachary Abramson, Yimei Li, Tushar Patni, Paul VanGilder, Akshay Sharma, Ranganatha Sitaram

Institution: St. Jude Children's Research Hospital

Language: English

Topic: Hemoglobinopathies and Related Disorders

Subfield: Genetics

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $5,190

Funders: American Lebanese Syrian Associated Charities, National Institutes of Health, National Cancer Institute, National Center for Research Resources

Awards: MRI Scanner (3T) for Research in Catastrophic Diseases of Childhood, G609259107, School Readiness Intervention for Preschool Children with Sickle Cell Disease, Cancer Center Support Grant (CCSG)

OpenAlex ID: W4415644081

FWCI: 0.524

Cites: 13

Cited by: 1

Related to: