Work

Severe systemic dissemination of copolyamide breast filler with multifocal abscess formation including mediastinal involvement: a case report

Year: 2025

Type: article

Abstract: Copolyamide-based hydrophilic fillers, such as Aquafilling, have been used off-label for breast augmentation; however, their long-term safety remains uncertain. Here, we report a rare case of a 26-year-old woman who developed widespread, recurrent soft-tissue abscesses and an anterior mediastinal fluid collection several years after a copolyamide breast filler injection. The patient required multiple surgical interventions and prolonged antibiotic therapy, highlighting the risk of severe delayed complications. This case underscores the importance of patient education, vigilant monitoring, and clinical caution, particularly in recognizing the potential for late-onset systemic dissemination and complications such as migration and infection associated with copolyamide breast filler injections.

Source: Archives of Aesthetic Plastic Surgery

DOI: 10.14730/aaps.2025.01501

Authors: Hyun Beom Choi, Woo Jin Song, Sang Gue Kang

Institutions: Soonchunhyang University, Soonchunhyang University Hospital Seoul

Language: English

Topic: Breast Implant and Reconstruction

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $60