Work

Follicular carcinoma of the thyroid with a single metastatic lesion in the skull: A case report

Year: 2025

Type: article

Abstract: Follicular thyroid carcinoma (FTC) represents a significant subset of thyroid malignancies following papillary thyroid cancer (PTC), constituting approximately 10% of all thyroid cancers. Surgical excision of metastatic lesions remains the cornerstone of treatment due to its potential for cure, symptom relief, and favorable response to radioactive iodine therapy. We present an exceedingly rare case involving a 79-year-old woman with a history of thyroidectomy 18 years prior, who presented to our hospital, Kashan Shahid Beheshti Hospital, with metastatic follicular thyroid carcinoma to the skull. FTC is characterized by early hematogenous spread, with the bone representing a typical site of metastasis. In patients diagnosed with FTC, large tumor size and presence of bone metastases are indicative of poor prognostic factors. However, the presence of a solitary bone metastasis should not preclude aggressive therapeutic interventions. Appropriate management strategies can lead to improved outcomes and enhanced quality of life for affected individuals.

Source: Radiology Case Reports

DOI: 10.1016/j.radcr.2025.08.037

Authors: Amir Hassan Matini, Sam Mirfendereski, Akram Tajoddini

Institutions: Kashan University of Medical Sciences, Isfahan University of Medical Sciences

Language: English

Topic: Thyroid Cancer Diagnosis and Treatment

Subfield: Endocrinology, Diabetes and Metabolism

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $600