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Combining Bioactive Cell-Penetrating Peptides and Vemurafenib to Produce Peptide–Drug Conjugates with Activity Against Drug-Resistant Melanoma Cells

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Year: 2025
Type: article
Source: Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.5c02367
Authors: Isabella R. Palombi, Andrew M. White, Yasuko Koda, David J. Craik, Sónia Troeira Henriques, Nicole Lawrence, Lara R. Malins
Institutions: Australian National University, Australian Research Council, The University of Queensland, ARC Centre of Excellence for Innovations in Peptide and Protein Science, Institute for Molecular Bioscience, Translational Research Institute, Queensland University of Technology
Language: English

Topic: Melanoma and MAPK Pathways
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: Australian Government, Snow Medical, Australian Research Council, National Health and Medical Research Council, Congressionally Directed Medical Research Programs
Awards: ARC Centre of Excellence for Innovations in Peptide and Protein Science, Advancing peptide-based drug design, G5368869171, G8663845830
OpenAlex ID: W4415648549
FWCI: 1.044
Cites: 57
Cited by: 4
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