Optimizing QACT Frequency in Proton Therapy: Analysis of Standard Guidelines Across Treatment Sites
Year: 2025
Type: article
Abstract: Purpose: Anatomical changes during proton therapy are typically monitored using quality assurance computed tomography (QACT) scans. However, excessive QACTs can increase patient burden, resource use, and health care costs. This study evaluates the impact of implementing standardized minimum QACT frequencies across treatment sites. Materials and Methods: -test was used to determine if the QACT rate was lowered after guideline implementation. A Wilcoxon signed rank test was used to determine if the adaptive planning rate was different before and after guideline implementation. Results: = .22), supporting that reduced QACT use did not compromise identifying needed treatment adaptations. CBCT was effective in identifying anatomical changes that prompted adaptive replanning in pelvis prostate patients. Conclusion: Establishing standard minimum QACT frequencies led to a significant reduction in the number of QACTs performed across several treatment sites. These findings support the utility of structured QACT guidelines to enhance resource efficiency and reduce patient burden in proton therapy.
Institutions: Johns Hopkins University, Johns Hopkins Medicine
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $1,700
Award: G2232272602
OpenAlex ID: W4415648563
