Effect of Vitamin D3 Supplements in the Success of Dental Implants: A Comparative Evaluation
Year: 2025
Type: article
Abstract: Background: Dental implants are a reliable treatment for tooth replacement, with success dependent on osseointegration, implant stability, and bone density. Vitamin D3 plays a critical role in bone metabolism, influencing calcium absorption and bone mineralization. However, the effect of vitamin D3 supplementation on implant outcomes remains controversial. Materials and Methods: A total of 20 patients with vitamin D deficiency (10-30 ng/mL) were divided into two groups: All patients underwent standard implant placement. Crestal bone level and bone density were assessed using CBCT, and implant stability was measured using resonance frequency analysis (RFA) at baseline, 3 months, and 6 months postimplant placement. Data were analyzed using ANOVA ( P < 0.05). Results: Implant stability improved significantly in Group A compared with Group B at 3 and 6 months ( P < 0.05). Crestal bone loss was higher in Group B, but the difference was not statistically significant ( P = 0.07). Bone density remained comparable between both groups at all time points ( P = 1.00). Conclusion: Vitamin D3 supplementation significantly enhances implant stability, suggesting a role in improving early-stage osseointegration. However, its effect on crestal bone level and bone density remains inconclusive. Preoperative vitamin D3 screening and supplementation in deficient individuals may optimize implant outcomes. Further large-scale studies are needed to establish definitive guidelines.
Authors: Nooka Surya Ramalakshmi, Gade Phani Krishna, D. Samyuktha, Deepthi Batthula, Jyothirmai Nagisetty, Jahnavi Valiveti
Language: English
Subfield: Oral Surgery
Field: Dentistry
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $250
OpenAlex ID: W4415655265