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Ultrasound-guided microwave ablation of granulomatous mastitis: An effective therapeutic tool

Year: 2025
Type: article
Study design: Observational Study
Abstract: Background: Granulomatous mastitis is a chronic inflammatory breast condition characterized by non-caseating granulomas in the breast tissue, often requiring multidisciplinary approaches for accurate diagnosis and effective management. This study aimed to evaluate the efficacy and safety of ultrasound-guided microwave ablation (MWA) for the treatment of granulomatous mastitis compared with surgical excision. Methods: This retrospective study analyzed the clinical outcomes of 65 consecutive patients with granulomatous mastitis treated with ultrasound-guided MWA (MWA group) and 60 patients treated surgically (surgery group) during the same period. Outcomes compared between the two groups included immediate effects, clinical cure rates, postoperative complication rates, recurrence rates, BREAST-Q satisfaction scores, and breast cosmetic score outcomes. Correlated variables were subsequently incorporated into a multivariate binary logistic regression model. Results: 16.7%, P<0.05). (III) The breast cosmetic score in the MWA group was significantly higher than that in the surgery group (P<0.05). (IV) Multivariate logistic regression analysis revealed that therapy method (MWA or surgery) and breast cosmetic score were significantly associated with complication rate. Conclusions: Ultrasound-guided MWA is safe and effective in the treatment of granulomatous mastitis, which can be used as an alternative treatment method.
Language: English
Field: Medicine
Open Access status: diamond
OpenAlex ID: W4415655950
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