Metagenome-assembled complete genome of Bohxovirus , a virulent bacteriophage involved in the prediction of hospital-acquired pneumonia in intubated critically ill patients
Year: 2025
Type: article
Abstract: ABSTRACT We present the complete genome of a Bohxovirus species, a virulent phage targeting Prevotella jejuni , reconstructed from viral metagenomes in respiratory endotracheal aspirates of intubated critically ill patients. The 98-kbp bacteriophage, belonging to the Suoliviridae family, does not contain genes associated with antibiotic resistance or bacterial virulence. CLINICAL TRIALS ClinicalTrials.gov numbers: NCT02003196 and NCT04793568 .
DOI: 10.1128/mra.00592-25
Institutions: Lyon 1 Université, École Normale Supérieure de Lyon, Centre National de la Recherche Scientifique, Inserm, Hospices Civils de Lyon, Virologie et Pathologies Humaines, Centre International de Recherche en Infectiologie, Center for Research in Transplantation and Translational Immunology, Nantes Université, Centre Hospitalier Universitaire de Nantes, The University of Melbourne, Peter Doherty Institute
Language: English
Subfield: Ecology
Field: Environmental Science
Domain: Physical Sciences
Open Access status: diamond
Funder: Horizon 2020 Framework Programme
Award: G4917897751
OpenAlex ID: W4415666729