Work

Functional identification of vagal afferent branch from the gastrointestinal organs by capsaicin administration in mice

Year: 2025

Type: article

Abstract: In a mouse study, we identified input patterns from the gastrointestinal organs and liver to vagal afferents, with physiological evidence that there is no one-to-one correspondence between nerve branches and organs; multiple nerve branches receive inputs from a single organ. This new discovery is important as it contributes to elucidating the mechanisms of physiological function based on the vagal afferent pathway affected by nutrition, osmotic pressure, and hormones.

Source: American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

DOI: 10.1152/ajpregu.00126.2025