Work

Percutaneous Radiofrequency Ablation After Incomplete Adrenalectomy in a Lateralized Case of Primary Aldosteronism

Year: 2025

Type: article

Abstract: Primary aldosteronism (PA) is a common cause of secondary hypertension. When unilateral aldosterone secretion is identified, surgery is the treatment of choice in most patients and is associated with a high cure rate. Alternative treatments, such as radiofrequency ablation (RFA), are possible options, particularly when surgery is contraindicated. A 56-year-old patient presented with hypertension secondary to PA. A left lateralization was identified after adrenal vein sampling, and the patient underwent a left laparoscopic adrenalectomy. Postoperatively, a residual adrenal remnant was detected incidentally on a computed tomography scan. Persistent PA was confirmed by hormonal workup. To avoid open laparotomy, RFA was proposed as an alternative treatment. The procedure was a biological success, leading to normalization of PA markers. Although adrenalectomy failure is rare, RFA appears to be a possible alternative treatment strategy to prevent the need for repeat surgery and its associated risks.

Source: JCEM Case Reports

DOI: 10.1210/jcemcr/luaf251

Authors: Pierre-Antonin Rigon, Nicolas Villard, Karim-Alexandre Abid, Tobias Zingg, Sandrine Eimer, Grégoire Wuerzner

Institutions: Centre Hospitalier Universitaire Vaudois, University of Lausanne

Language: English

Topic: Hormonal Regulation and Hypertension

Subfield: Endocrinology, Diabetes and Metabolism

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $930