Work

CRISPR/Cas9 library screening uncovered CCT2 as a critical driver of acquired resistance to EGFR-targeted therapy by stabilizing TMX1 in non-small cell lung cancer

Year: 2025

Type: article

Source: Cell Death and Differentiation

DOI: 10.1038/s41418-025-01600-w

Authors: Zihao Ke, Qi Zhang, Xingyu Chen, Rongrong Jin, Gaohua Han, Qianhua Cao, Ke Zhu, Shihui Wei, Jiajin Chen, Qian Wang, Meiling Zhang, Weina Huang, Kaimin Li, Kunlong Xiong, Kaihua Lu, Ying Chen, Chao Cao

Institutions: Ningbo University, The Affiliated Taizhou People's Hospital of Nanjing Medical University, Nanjing Medical University, Jiangsu Province Hospital

Language: English

Topic: Lung Cancer Treatments and Mutations

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W4415710203

FWCI: 0.593

Cites: 39

Cited by: 1

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