Work

A human-specific RPGR isoform and a clinically approved Rho/ROCK inhibitor ameliorate defects associated with RPGR dysfunction

Year: 2025

Type: article

Abstract: -associated retinal degeneration.

Source: Molecular Therapy — Nucleic Acids

DOI: 10.1016/j.omtn.2025.102758

Authors: Muhammad Usman, Paul Atigbire, Dennis Kastrati, Julia Milena Brinkhoff, Charlotte Luise Kluth, Jannis Marticke, Christoph Jüschke, John Neidhardt

Institution: Carl von Ossietzky Universität Oldenburg

Language: English

Topic: Retinal Development and Disorders

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,900

Funders: School of Medicine and Health Sciences, European Commission, Deutsche Forschungsgemeinschaft

Awards: G1072234197, G1655101411, G7522363224

OpenAlex ID: W4415727020

FWCI:

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