Work

A mediastinal eosinophilic adenoma misdiagnosed as an esophageal stromal tumor: A case report

Year: 2025

Type: article

Abstract: BACKGROUND: Eosinophilic adenoma, a benign tumor characterized by eosinophilic cell proliferation, typically arises in endocrine organs such as the thyroid or parathyroid glands. Ectopic parathyroid eosinophilic adenoma is rare and may mimic other mediastinal pathologies, leading to diagnostic challenges. CASE PRESENTATION: We present a case of a 54-year-old woman with a one-year history of dysphagia. Initial imaging and endoscopic studies suggested an esophageal stromal tumor. Thoracoscopic resection revealed a posterior mediastinal mass, later confirmed as an ectopic parathyroid eosinophilic adenoma through histopathological and immunohistochemical analysis. CONCLUSIONS: This case underscores the importance of integrating imaging, laboratory tests, and histopathology for accurate diagnosis of mediastinal masses. Minimally invasive thoracoscopic surgery proved effective for resection, highlighting the need for tailored therapeutic approaches. In order to avoid such misdiagnosis, clinicians should make a definite pathological diagnosis before surgery as much as possible.

Source: Journal of Cardiothoracic Surgery

DOI: 10.1186/s13019-025-03666-6

Authors: Siyu Chen, Jusi Wang, Ning Ao, Shouyin Di, Hui Wu, Taiqian Gong

Institution: Chinese PLA General Hospital

Language: English

Topic: Myasthenia Gravis and Thymoma

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,890