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Multiple relapses of mantle cell lymphoma as different extranodal lesions: A case report

Year: 2025

Type: article

Abstract: Mantle cell lymphoma (MCL) usually affects the lymph nodes; however, extranodal involvement is also common, particularly in Waldeyer's ring and the gastrointestinal tract, spleen and bone marrow. Other organs that may be affected include the skin, endocrine glands, lungs and central nervous system, with these sites most commonly affected by relapsing disease. However, in rare, extranodal MCL has arisen in the ocular adnexa, soft tissue and heart. The present study reports the case of a 75-year-old male patient, who experienced repeated relapses of MCL, involving ocular adnexa, soft-tissue and cardiac lesions, which are rare. The aim of the present case report was to demonstrate that clinicians should be aware of the various extranodal sites at which MCL can arise, and monitor patients carefully during and after treatment.

Source: Medicine International

DOI: 10.3892/mi.2025.284

Authors: Masahiro Manabe, Daisuke Aohara, Daiki Mukai, Satoru Nanno, Ki-Ryang Koh

Institutions: Osaka General Hospital Of West Japan Railway Company (Japan), Osaka City General Hospital

Language: English

Topic: Lymphoma Diagnosis and Treatment

Subfield: Pathology and Forensic Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4415728423

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