Work

Severe tophaceous gout in the setting of myelofibrosis: A clinical challenge

Year: 2025

Type: article

Abstract: We illustrate a case of a patient with a history of myelofibrosis, presenting with a clinical picture of presumed infection. Imaging revealed apparent fluid collections and erosions in the ankle/foot, supporting the clinical suspicion of infection. However, operative findings revealed extensive tophaceous gout, likely a consequence of long-standing myelofibrosis. It is important to be aware of this atypical presentation of gout in patients with myelofibrosis.

Source: Radiology Case Reports

DOI: 10.1016/j.radcr.2025.09.080

Authors: Nicole Chin, Aidan Megally, Omar Zahra, Akshita Gorantla, Shravika Talla, Emad Allam

Institutions: Loyola University Medical Center, Loyola University Chicago

Language: English

Topic: Gout, Hyperuricemia, Uric Acid

Subfield: Nephrology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $600