Work

A lab-on-a-chip system integrating DNA purification and loop-mediated isothermal amplification for the quantification of the toxic diatom Pseudo-nitzschia multistriata

Year: 2025

Type: article

Abstract: A microfluidic system using DMA-based DNA purification for toxin-producing algae, combined with air-dried LAMP reagents stable at room temperature for up to five months, enables rapid and low-cost detection without the need for cold storage.

Source: Sensors & Diagnostics

DOI: 10.1039/d5sd00135h

Authors: Ahmed I. Alrefaey, Jonathan S. McQuillan, Allison Schaap, Fabrizio Siracusa, Christopher L. Cardwell, John Walk, Daniel Rogers, Reuben Forrester, Matthew C. Mowlem, Julie C. Robidart

Institutions: National Oceanography Centre, University of Southampton

Language: English

Topic: Biosensors and Analytical Detection

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Clean water and sanitation

Open Access status: diamond

Funders: UK Research and Innovation, European Commission, Stazione Zoologica Anton Dohrn, National Oceanography Centre, Horizon 2020 Framework Programme

Awards: G1989846580, G2278340370, G434337789, G6662901448, Atlantic ECOsystems assessment, forecasting & sustainability, Technologies for Ocean Sensing

OpenAlex ID: W4415733944

FWCI: 0.716

Cites: 53

Cited by: 3

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