Novel Colorimetric Anthracene-Based Thiosemicarbazone Probe for Selective Cyanide Ion Detection: From Synthesis to Real-Time Applications
Year: 2025
Type: article
Abstract: High Resolution Image Download MS PowerPoint Slide A novel thiosemicarbazone, N ’-(anthracen-9-ylmethylene) morpholine-4-carbothiohydrazide ( MA ), was synthesized and characterized for selective cyanide ion sensing. Interaction between the cyanide ion and sensor MA was examined thoroughly with the aid of absorption, emission, and 1 H NMR spectra, and the binding constant was estimated. The detection limit obtained was much lower than those reported recently. The 1 H NMR spectra titration studies clearly indicated that deprotonation occurs from the N–H group of the receptor. The sensing mechanism was further explored by density functional theory (DFT) and time-dependent DFT (TDDFT) methods using Gaussian16 software. In silico investigation reveals that the added cyanide ion abstracts a proton from the N–H group, which supports experimental results. The synthesized receptor MA was found to be a very good candidate for selective sensing of cyanide.
Source: ACS Omega
Institution: VIT-AP University
Language: English
Subfield: Spectroscopy
Field: Chemistry
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $1,935
OpenAlex ID: W4415740844