Utilization of interdisciplinary in-hospital early rehabilitation in COVID-19 patients - a multicenter cohort study in the National Pandemic Cohort Network (NAPKON) in Germany
Year: 2025
Type: article
Study design: Observational Study
Abstract: BACKGROUND: Early rehabilitation in acute hospitals aims to prevent immobilization-related complications and improve the functional capacity of patients with severe or critical illness. Early rehabilitation can be a useful concept to improve functioning in COVID-19 patients. However, literature concerning early in-hospital rehabilitation in COVID-19 patients is scarce. AIM: To analyze the utilization of in-hospital interdisciplinary early rehabilitation (IER) in COVID-19 patients and characterize the sample of IER patients. DESIGN: Prospective cohort study. SETTING: Hospitalized COVID-19 patient cases. POPULATION: This study used data from the National Pandemic Cohort Network (NAPKON) in Germany. METHODS: IER utilization rates were retrieved. Demographic and clinical data from hospitalized COVID-19 patients who had received IER during the course of their treatment were evaluated. RESULTS: Out of the 2,644 patients in the Cross-Sectoral Platform (German abbreviation: SUEP) cohort, 0.79% [95% CI: 0.51% to 1.22%] received IER during their stay in an acute care hospital. Among the subgroup of patients who had previously been treated in intensive care, 2.13% [95% CI: 1.16% to 3.63%] received IER. The most common comorbidities were cardiovascular diseases (66.7%) and neurological/psychiatric diseases (36.1%). The small sample size limited further analyses. CONCLUSION: The low rate of early rehabilitation in acute hospitals for COVID-19 patients indicates an unmet need, particularly in severe cases. Structural changes in the health system are needed to close this gap. The WHO and the German Medical Council have recently acknowledged the necessity of early in-hospital rehabilitation and have issued a call for its implementation in acute hospitals.
Source: PLoS ONE
Authors: Max E. Liebl, Anett Reisshauer, Dana Loudovici-Krug, Philipp Baumbach, Katharina S. Appel, Sabine Blaschke, Johanna Erber, Ilka Grewe, Marina Hagen, Ekaterina Heim, Sina M. Pütz, Kristin Lehnert, Patrick Meybohm, Olga Miljukov, Milena Milovanovic, Susana M. Nunes de Miranda, Christoph Römmele, Phil-Robin Tepasse, Jörg J. Vehreschild, Norman Weinert, Martin Weigl, Julia Wendel, Christina Lemhöfer
Institutions: Humboldt-Universität zu Berlin, Charité - Universitätsmedizin Berlin, Jena University Hospital, Friedrich Schiller University Jena, Goethe University Frankfurt, Universitätsmedizin Göttingen, University of Göttingen, TUM Klinikum, Technical University of Munich, University Medical Center Hamburg-Eppendorf, Universitätsmedizin Greifswald, Universität Greifswald, University of Cologne, University Hospital Cologne, German Centre for Cardiovascular Research, Universitätsklinikum Würzburg, University of Würzburg, University of Augsburg, University Hospital Augsburg, University Hospital Münster, German Center for Infection Research, LMU Klinikum, Ludwig-Maximilians-Universität München
Language: English
Field: Health Professions
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,382
Funders: Pfizer, Gilead Sciences, Deutsches Zentrum für Infektionsforschung, Bundesministerium für Bildung und Forschung, Astellas Pharma, Universitätsklinikum Regensburg, Universität des Saarlandes, Medizinischen Hochschule Hannover, Universität Bielefeld, RWTH Aachen University, Julius-Maximilians-Universität Würzburg, Uniklinikum Giessen und Marburg, Universitätsklinikum Köln
OpenAlex ID: W4415748338