Clinico-demographic Profile of Patients with Early Primary Open Angle Glaucoma at a Tertiary Private Eye Hospital in Lagos, Nigeria
Year: 2025
Type: article
Study design: Observational Study
Abstract: Background: This study aimed to characterize the clinical and sociodemographic profiles of Nigerian patients with early-stage primary open-angle glaucoma (POAG), with the goal of highlighting the significance of timely diagnosis in enhancing glaucoma treatment outcomes. Methodology: This cross-sectional study involved participants aged ≥ 40 years with early POAG. The participants underwent a slit-lamp examination of the anterior and posterior segments. The examination included gonioscopy, after which only eyes with open angles were selected. A central visual field test was conducted, and one eye of each participant who met the criteria for early POAG was selected for optical coherence tomography/angiography test (OCT/A). The relevant data were analyzed using the Statistical Package for Social Sciences (SPSS) version 26, with statistical significance set at p<0.05, with a 95% confidence interval. Results: There were 90 participants with a mean age of 54.5 ± 10.1 years, comprising 54 males (60%). All participants had a best-corrected visual acuity (BCVA) of at least LogMAR 0.48, and the mean central visual field (CVF) MD was -3.50 ± 1.0 dB. The mean retinal nerve fiber layer (RNFL) thickness was 97.79 ± 17.33. The mean peripapillary vessel density (VD) was 50.21 ± 4.54%. Nearly half (47.8%) of the participants had other systemic medical conditions, primarily hypertension or hyperlipidemia. Conclusion: Patients with early POAG were asymptomatic and had good visual acuity and minimal RNFL thickness reduction. This highlights the importance of routine hospital screening of people 40 years and older to aid early diagnosis of POAG.
Source: PubMed
Institutions: Eye Foundation Hospital, University of Port Harcourt
Language: English
Subfield: Ophthalmology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W4415764446
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