Figure 1 from Decoding the Genomic and Functional Landscape of Emerging Subtypes in Ovarian Cancer
Year: 2025
Type: other
Abstract: Study and signature overview. A, Schematic summary of the data and integration workflow. B, Feature summary: median of the value of each feature in the cohort, with error bars representing the quantiles 0.25 and 0.75. The features are colored according to the feature class and displayed in the boxes above the distribution. Feature classes derived from continuous features are connected below, with their distributions transformed on log scale. Colors match classes in A. The red dashed lines represent discretization thresholds determined using the Jenks natural breaks algorithm. CNV, copy number variant; LINE, long interspersed nuclear elements; SV, structural variant. C, Feature profiles of extracted signatures, derived with SigProfilerExtractor and using the features in A. The signatures exhibit distinct patterns, emphasizing their differences, and can be further observed in the interactive visualization at GenomeSpy_2.
Language: English
Subfield: Reproductive Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4415786922