Supplementary Figures S1-S9 from Decoding the Genomic and Functional Landscape of Emerging Subtypes in Ovarian Cancer
Year: 2025
Type: supplementary-materials
Abstract: Supp. Fig. S1 shows signature robustness. Supp. Fig. S2 displays the association of all signatures with homologous recombination and BRCA1/2 mutations. Supp. Fig. S3 depicts the association of signatures with whole genome duplication, amplification of CCNE1, KRAS, MYC, and MECOM and the relationship with survival. Supp. Fig. S4 shows how complex structural variants manifest and in which signatures they are prevalent. Supp. Fig. S5 explains the SCN-G segmentation aberration. Supp. Fig. S6 presents the validation dataset results in terms of survival and genomic characteristics. Supp. Fig. S7 displays transcriptomics analysis results for the proliferative HRP subtype. Supp. Fig. S8 depicts the transcriptomic results for the EMTHRP subtype. Supp. Fig. S9 contains the results from the transcriptomic analysis for the core HRP subtype.
Language: English
Subfield: Reproductive Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4415786970