Diagnostic Pitfall of Lytic Bone Lesions: A Case of Chromophobe Renal Cell Carcinoma Coexisting With Multiple Myeloma
Year: 2025
Type: article
Study design: Case Report
Abstract: The coexistence of renal cell carcinoma (RCC) and multiple myeloma (MM) is rare and presents a significant diagnostic challenge, particularly when patients present with back pain and lytic bone lesions. Several case series and reports have documented a reciprocal relationship between the two malignancies, which may be attributed to shared etiological factors, analogous cytokine-mediated growth mechanisms, and converging clinical presentations. We report the case of a 66-year-old man diagnosed with chromophobe RCC who presented with persistent back pain and was ultimately diagnosed with coexisting MM.
Source: Cureus
DOI: 10.7759/cureus.95985
Authors: Aaeshah M Almutairi, Omar Abusedera, Adnan M Shaheen
Institution: Royal College of Surgeons in Ireland - Bahrain
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4415788217