Changes in emotional dysregulation profile among offspring of parents with bipolar disorder: a family-based intervention pilot study
Year: 2025
Type: article
Study design: Clinical Trial
Abstract: Offspring of parents with bipolar disorder (OBD) are at increased risk for mood and behavioral disorders, with emotional dysregulation being an early marker. This pilot study aimed to evaluate the effect of a family-focused intervention on emotional dysregulation in OBD, hypothesizing a significant reduction in CBCL Emotional Dysregulation Profile scores over 12 months. Twenty-five OBD aged 6-16 years participated in a four-session psychoeducational program. Significant reductions were observed in CBCL emotional dysregulation scores suggesting that a brief family-focused program may reduce dysregulation and improve functioning in OBD. TRIAL REGISTRATION NUMBER: Clinicaltrials.gov. ID NCT03299140. Registered on the 17th September, 2017.
Institutions: Inserm, Université de Versailles Saint-Quentin-en-Yvelines, Centre Hospitalier Universitaire de Montpellier, Centre de recherche en Epidémiologie et Santé des Populations, Hôpital Saint Eloi, Centre National de la Recherche Scientifique, Hôpital Lapeyronie, Institut de Génomique Fonctionnelle
Language: English
Subfield: Psychiatry and Mental health
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,990
OpenAlex ID: W4415788692