Work

Intracavitary infusion of FOLactis Lactobacillus leads to disappearance of MPE in patient with advanced lung adenocarcinoma

Year: 2025

Type: article

Abstract: This case report presents the application of FOLactis, a lactic acid bacterium in situ vaccine, in the treatment of a lung adenocarcinoma patient who presented with malignant pleural effusion (MPE). An adult patient diagnosed with lung adenocarcinoma complicated by malignant pleural effusion (MPE) experienced favorable outcomes following the administration of intracavitary infusion of FOLactis, as conventional therapeutic approaches failed to yield satisfactory results. One month after the administration of FOLactis treatment, a subsequent CT examination revealed the complete resolution of malignant pleural effusion (MPE).

Source: Discover Oncology

DOI: 10.1007/s12672-025-03727-1

Authors: Mingzhen Zhou, Juan Zhang, Sihui Zhu, Yan Zhao, Baorui Liu, Jie Shen

Institutions: Nanjing University of Chinese Medicine, Nanjing Drum Tower Hospital, Nanjing University

Language: English

Topic: Pleural and Pulmonary Diseases

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,690