Novel 2 H -Pyrazolo[3,4- d ]thiazole Compounds Targeting NLRP3 for the Treatment of Neurodegenerative Diseases
Year: 2025
Type: editorial
Abstract: High Resolution Image Download MS PowerPoint Slide The invention discloses novel NOD-, LRR-, and pyrin domain-containing protein 3 (NLRP3) inhibitors featuring a 2 H -pyrazolo[3,4- d ]thiazole scaffold. These NLRP3 inhibitors exhibit significant potential as therapeutic candidates for neurodegenerative diseases, including Alzheimer’s disease and Parkinson’s disease.
Source: ACS Medicinal Chemistry Letters
Authors: Zhendong Song, Steven H. Liang
Institution: Emory University
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W4415822673