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Discovery of Novel Class of METTL3 Inhibitors with a Pyridin-2(1 H )-one Moiety

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Year: 2025
Type: article
Source: ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.5c00465
Authors: Weihang Zhang, Yuting Huang, Hong Yang, Haiyan Wan, Xinsheng Lei, Jinxi Xiang, Yujie Wang, Yingxia Li, Xun Huang, Yu Sun
Institutions: Fudan University, Shanghai Jiao Tong University, Chinese Academy of Sciences, Shanghai Institute of Materia Medica, State Key Laboratory of Drug Research, East China University of Science and Technology
Language: English

Topic: RNA modifications and cancer
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: National Natural Science Foundation of China, Program of Shanghai Subject Chief Scientist
Awards: G5108145204, G6248166582
OpenAlex ID: W4415837414
FWCI: 0.505
Cites: 29
Cited by: 2
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