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Binocular visual function of Japanese eyes with nondiffractive extended depth-of-focus intraocular lenses made of high water-content hydrophobic acrylic material

Year: 2025

Type: article

Abstract: PURPOSE: To prospectively evaluate bilateral visual function in Japanese patients implanted with nondiffractive extended depth-of-focus (EDoF) intraocular lenses (IOLs). STUDY DESIGN: Multisite prospective observational study. PATIENTS AND METHODS: This study included 48 eyes of 24 Japanese patients with cataracts (mean age: 68.7 ± 9.2 years) who underwent bilateral implantation of nondiffractive EDoF IOLs CNAET0 (Clareon Vivity, Alcon), made of high-water-content hydrophobic acrylic material. Three months postoperatively, binocular uncorrected and distance-corrected visual acuities (BUCVA and BDCVA) were assessed at far, 66 cm, and 40 cm. Binocular photopic contrast sensitivity (CSV-1000), binocular defocus curves, spectacle independence, and photic phenomena (glare, halo, starburst, and waxy vision) were also assessed. RESULTS: The mean logMAR BUCVA/BDCVA was -0.11/-0.15 at far, 0.05/0.08 at 66 cm, and 0.18/0.22 at 40 cm. Binocular contrast sensitivity was within the normal range for individuals aged 60-69 years across all spatial frequencies. The mean defocus curve demonstrated 0.1 logMAR or better between -2.0 and +1.0 D addition, with better performance of 0.0 logMAR or better between -1.5 and +0.5 D addition. All patients were spectacle-independent for distance and intermediate vision, whereas nine of the 24 patients (37.5%) required spectacles for near vision. None of the patients reported severe photic phenomena; 17 patients (70.8%) did not experience glare or starburst, and 20 patients (83.3%) did not report halo or waxy vision. CONCLUSION: Bilateral implantation of nondiffractive EDoF IOLs provided good binocular functional vision from far to near, although some patients may require spectacles for near vision. The photic phenomenon was minimal.

Source: Japanese Journal of Ophthalmology

DOI: 10.1007/s10384-025-01300-5

Authors: Hisaharu Suzuki, Yuka Ota, Seiichiro Hata, Keiichiro Minami, Hiroko Bissen-Miyajima

Institution: Tokyo Dental College Suidobashi Hospital

Language: English

Topic: Intraocular Surgery and Lenses

Subfield: Ophthalmology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,790