A Study of the Clinical Profile of Gastrointestinal and Primary Splenic Lymphoma Cases at a Tertiary Care Hospital
Year: 2025
Type: article
Study design: Observational Study
Abstract: Background: Gastrointestinal lymphomas are the most common extranodal lymphomas, while primary splenic lymphomas remain rare and diagnostically challenging. To eva Objectives: luate the clinical features, diagnostic findings, and treatment outcomes of gastrointestinal and primary splenic lymphomas in a tertiary care hospital. Twenty patient Methods: s with histologically confirmed non-Hodgkin lymphoma involving the gastrointestinal tract or spleen were analyzed. Clinical presentation, investigations, histology, and outcomes were studied. Diffuse large B-cell lymphoma was Results: the predominant subtype. PET-CT and endoscopy were valuable diagnostic tools. Patients treated with combined surgery and chemotherapy had better survival compared to those receiving chemotherapy alone. PET-CT–based staging showed significant correlation with improved prognosis (p=0.047). Early diagnosis and multimodality manageme Conclusion: nt improve outcomes in gastrointestinal and splenic lymphomas. PET-CT serves as an important aid in evaluation and follow-up.
Authors: Riddhima Dubhashi, Suresh Kumar Palanichamy, Chinni Vikram Asokan, Sankar Subramanian, Akhil Chowdari Ganamani
Language: English
Subfield: Pathology and Forensic Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4415855763
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