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Editorial Expression of Concern: Metabolic remodelling produces fumarate via the aspartate–argininosuccinate shunt in macrophages as an antiviral defence

Year: 2025

Type: editorial

Abstract: The Editors would like to alert the readers that concerns have been raised regarding the source data for Fig. 1d and e, where a number of samples in different groups show identical values. Further checks by the Publisher identified high similarity between Extended Data Fig. 6g middle panel, Actin lanes 1–3 and Extended Data Fig. 7g right panel, Actin lanes 2–4, which represent different treatments. The latter concern has been addressed by a correction 1 , but the authors have been unable to provide a satisfactory explanation for the source data similarities.

Source: Nature Microbiology

DOI: 10.1038/s41564-025-02195-1

Authors: Wenjun Xia, Youxiang Mao, Ziyan Xia, Jie Cheng, Peng Jiang

Institutions: Center for Life Sciences, State Key Laboratory of Molecular Oncology, Tsinghua University, Huazhong University of Science and Technology

Language: English

Topic: interferon and immune responses

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $12,690