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Rational Leucine-Centric Design Confers Enhanced Proteolytic Stability and Reduced Toxicity of Antimicrobial Peptides against Multidrug-Resistant Bacterial Infections

Year: 2025

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.5c01877

Authors: Shuyuan Jiang, Wenpeng Zhang, Long Tian, Chunlan Zeng, Jiaqi Han, Xia Wu, Yijie Xu, Longming Chen, Jiangmin Zeng, Chunhui Zhao, Li Zhang, Liang Luan, Weifeng Ye, Changhao Zhang, Taoran Wang, Qingbin Meng

Institutions: Yanbian University, Academy of Military Medical Sciences, General Hospital of Shenyang Military Region, Capital Medical University, Beijing Friendship Hospital

Language: English

Topic: Antimicrobial Peptides and Activities

Subfield: Microbiology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W4415890874

FWCI: 0.464

Cites: 61

Cited by: 1

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